Doing a colposcopic biopsy some patients feel no pain, there may be a slight soreness; a small number of patients are more sensitive to pain, there may be a slight pain. Colposcopic biopsy is generally taken from the cervical opening of the tissue, but the cervix does not have the distribution of somatic sensory nerves, so in the colposcopic biopsy, and will not feel obvious pain, there is generally some soreness and discomfort, if the pain is very sensitive to the pain of the person, then there may be a slight pain, but also can be tolerated. After colposcopy biopsy may also appear localized small amount of bleeding, bleeding period to avoid coitus. Avoid intercourse during the bleeding period so as not to increase the risk of infection. If there is any abnormality after the biopsy, it is recommended to seek medical attention.