A severe crooked face may be caused by mumps, occlusal hypertrophy, first and second gill arch syndrome, cranial dysplasia, etc., which need to be treated with medication and surgery. 1. Mumps: If the size of the face is caused by mumps, and the patient has a serious crooked face. Patients can use antiviral drugs such as ribavirin under the guidance of doctors, and for patients with high fever, they can use antipyretic drugs such as ibuprofen and acetaminophen as prescribed by doctors. 2. Bite muscle hypertrophy: For the bite muscle hypertrophy caused by the size of the face crooked face serious, can be injected with botulinum toxin to make the local bite muscle shrinkage. In addition, patients with occlusal hypertrophy can also be surgically removed from the side of the mouth excess occlusal muscle, which can also make the face size to restore consistency. 3. The first and second gill arch syndrome: If the first and second gill arch syndrome leads to a serious crooked face, it can be treated with surgical procedures such as mandibular ascending sagittotomy and chinoplasty. 4. Cranial dysplasia: for the cranial dysplasia caused by large and small crooked face, you can take mandibular grinding, bone cement filling, zygomatic bone grinding and other plastic surgery to rebuild the facial skeleton scaffolding. It is recommended that patients who have a crooked face need to consult a doctor in a timely manner, and the doctor will choose the appropriate measures according to the cause of the treatment.