A fornix-like defect is a nodule-like substance, sometimes painful to the touch, that can be palpated by the doctor in the posterior fornix, the area of the posterior vaginal fornix, between the cervix and the rectum, during a gynecological examination. If the nodule is painful and worsens with the menstrual cycle, endometriosis may be present. A fornix-like defect is not a complete confirmation of endometriosis, and the diagnosis has to be made based on a combination of history, symptoms and a combination of other gynecological examinations laboratory tests and imaging tests. If the diagnosis of endometriosis is confirmed by examination, non-steroidal anti-inflammatory drugs such as indomethacin and ibuprofen can be used under the supervision of a doctor to reduce pain, and progestins such as medroxyprogesterone acetate, medroxyprogesterone or norethindrone can also be used. The appearance of fornix-like defects, you should promptly go to the hospital, with the help of the hospital to improve the examination, to clarify the cause of the disease and targeted treatment.