Thigh muscle soreness after rabies vaccination belongs to the normal adverse reactions after vaccination, and can be relieved by massage, hot compresses and other ways to relieve muscle soreness symptoms. After rabies vaccination, the body may have some adverse reactions, including arthralgia, muscle pain, mild fever, chills, gastrointestinal dysfunction, headache, dizziness and other systemic reactions. When the body has an adverse reaction of muscle pain, usually the symptoms can be relieved or subside within 1 to 3 days, and there is no need to worry too much. Massaging the sore area or applying hot compresses with a towel on the sore area can promote local blood circulation and improve muscle soreness. In addition, if the muscle soreness does not subside after more than 3 days, it is recommended to go to the hospital for examination and timely treatment.