Patients with hypertension mainly apply antihypertensive drugs to control their blood pressure, and pulse-particles are mainly applied for people with coronary heart disease. If patients do not have severe atherosclerosis and coronary heart disease, the application of methotrexate particles is not recommended. Patients with hypertension have a certain risk of complications such as coronary heart disease and stroke, but these atherosclerotic diseases can be prevented if patients can actively control their blood pressure, as well as use drugs like aspirin and lipid-lowering drugs for secondary prevention of coronary heart disease and stroke on the basis of controlling risk factors. The pulse pellets are mainly used for people with definite coronary heart disease and ischemic cardiomyopathy, and are not recommended for hypertensive patients without a history of combined heart disease.