Photoreactivity screening is an assessment of the presence or absence of photopsia in newborns at the time of full-term health management, which allows for early detection and intervention. Before the age of 6 years, children’s visual function and eye structure development is critical, especially after the birth of newborns need to carry out the full-month health management, which includes the light response test to assess the newborn’s photoreceptor. As the name suggests, the photoreactivity test involves the examiner moving a flashlight quickly in front of the infant’s eyes to illuminate the pupil area and repeating the test several times, with both eyes tested in turn. When the infant shows reflexive eye closure after illumination, it is considered normal, indicating that the infant has light perception in the eyes. During the developmental stage of visual function, the relevant examination should be improved as early as possible to achieve early detection and early intervention. When there are abnormalities in the light response test or visual acuity, it is important to pay close attention and go to a specialist clinic to identify the cause of the problem.