Interstitial pneumonia of more than 20 years belongs to chronic interstitial pneumonia, and its treatment mainly includes keeping away from triggers, medication, lung transplantation and other aspects of treatment. 1. Keep away from triggers: Try to keep the air as fresh as possible, especially during the relatively polluted air quality, do not travel unless necessary, and wear a mask when going out to reduce the stimulation of pollution to the lungs. 2. Drug therapy: the application of glucocorticoids can well inhibit the inflammatory response of the lungs, the treatment can be combined with immunosuppressants and antifibrotic drugs, should be used under the guidance of a doctor. 3. Surgery: For patients who are not well treated by internal medicine, surgery, i.e. lung transplantation, can be considered if there are indications, but the indications and contraindications need to be carefully grasped. 4. Other treatments: Follow the vaccination program to receive influenza and pneumonia vaccines, which can stimulate the body to produce antibodies, improve immunity, reduce the probability of developing respiratory diseases, and reduce the pressure on the lungs. In addition, oxygenation is an important measure to improve the quality of life. For patients who have had the disease for more than 20 years, it is important to meet the basic nutritional requirements and do some exercise under the guidance of your doctor to improve your physical fitness to improve lung function. If you feel unwell, please seek medical help as soon as possible.