Cold medicine and amoxicillin can be taken together. Cold medicines are medicines to relieve cold symptoms, amoxicillin belongs to penicillin antibiotics, the two together can improve the efficacy and shorten the course of the disease; colds should drink more water and rest can speed up the healing. 1. Cold and flu medicines are mostly compound preparations, with antipyretic and analgesic, contraction of nasal mucosal blood vessels, can relieve dizziness, headache, fever, sore throat, nasal congestion, sneezing and general body aches and other cold and flu symptoms. 2. Amoxicillin belongs to penicillin antibiotics, if the cold combined with bacterial infection, you can apply amoxicillin for anti-infection treatment. But be careful: always ask for a history of allergies before using it. The side effects of the drug include nausea, vomiting, diarrhea and itchy skin; it is forbidden for those who are allergic to the ingredients of the drug. If there is any discomfort, it is recommended that the patient go to a regular hospital for consultation and treatment, and not blindly self-medication, so as not to delay the condition.