Statins are lipid-lowering drugs of the statin class, which are commonly used in clinical practice to lower blood lipids and treat hyperlipidemia. There are many kinds of lipid-lowering drugs that can be used in clinical practice, among which there are mainly statins and betablockers, and statins include simvastatin, pravastatin, atorvastatin, and resevastatin, which have in common the ability to effectively lower cholesterol levels and LDL levels. However, statins also have certain side effects, such as chronic liver insufficiency when taken for a long time. In addition, prolonged use of statins can lead to indigestion such as diarrhea, constipation and abdominal pain. Therefore, for statins, it is important to monitor the patient’s liver function regularly when taking them. Especially in patients with chronic liver insufficiency, they should not be used or used with caution as much as possible.