Irbesartan and Piperazine Ferulate Tablets can reduce urinary protein to some extent. Irbesartan reduces protein spillage mainly by lowering blood pressure; Piperazine Ferulate Tablets reduce urine protein production mainly by dilating renal blood vessels. 1. Irbesartan: Irbesartan is a selective angiotensin-II receptor antagonist, which can effectively reduce the action of renin-angiotensin on the vasculature, so that the vasodilatation of blood vessels, blood pressure is reduced, and to reduce intraglomerular high pressure, hyperperfusion and hyperfiltration, to slow down the glomerulosclerosis and renal protection, the first choice of drugs for the treatment of chronic nephritis hypertension and (or) proteinuria. 2. Piperazine Ferulic Acid Tablets: Piperazine Ferulic Acid Tablets have the effects of anticoagulation and dilation of microvessels. Improve renal circulation, can reduce the production of urinary protein. However, it is mainly for auxiliary treatment. All of the above medications should be used under the guidance of a doctor, avoid self-medication. If the patient has urine protein, it is recommended to go to the regular hospital in time, improve the examination to clarify the cause of the disease, under the guidance of the doctor to give targeted treatment or treatment.