Helicobacter pylori (HP) infection in children has been on the rise in recent years and is causing concern. What are the symptoms of HP infection in children? What are the symptoms of HP infection in children and how do they differ from adults and how should they be treated? Today, we share with you the knowledge of HP infection in children. 1, first of all, what is H. pylori? What are the dangers of it? Helicobacter pylori is a spiral-shaped bacterium that exists in the human stomach and is one of the few bacteria that can survive in a strong acidic environment like stomach acid, hence its name. Hp infection can cause gastritis, gastric ulcer, and in adults it can even develop into gastric cancer. 2.What are the Hp detection methods? Non-invasive means: carbon 13 breath test, serological test, stool antigen test; invasive tests: gastroscopic rapid urease test, gastric mucosal smear, bacterial culture, etc. 3. Under what circumstances do children need to be tested for HP? (1) peptic ulcer; (2) lymphoma of gastric mucosa-associated lymphoid tissue; (3) chronic gastritis; (4) children with gastric cancer in first-degree relatives; (5) unexplained refractory iron deficiency anemia; (6) those who plan to take non-steroidal anti-inflammatory drugs for a long period of time It is important to note that unlike adults, the purpose of HP testing in children is to find the underlying cause, not to 4.What are the Hp eradication treatment options? First-line eradication program: ①amoxicillin + clarithromycin + omeprazole ②amoxicillin + metronidazole + bismuth Second-line eradication program: ①bismuth quadruple therapy ②companion therapy 5.How to judge the efficacy of eradication? Generally, Hp test is performed 1 month after stopping the eradication treatment, and if the positive test turns to negative, the eradication is successful. It should be noted that within 1 month after stopping the drug, avoid taking antibiotics, PPI and other drugs that may affect the test results. 6.How to prevent Hp infection in children? Since Hp infection is mainly through the fecal-oral route, children can be infected by eating together with Hp infected people, so if there are Hp infected people in the family, it is more important to pay attention to the protection of children.