H. pylori infection may cause high fever. H. pylori infection may be caused by living with a person who has H. pylori infection, unclean drinking water, and other causes. Patients may experience symptoms such as bloating, belching, anorexia, acid reflux, and heartburn. With the development of the disease can also appear the phenomenon of pyloric obstruction, which can cause patients to experience repeated vomiting, electrolyte disorders, which can lead to high fever. Therefore, H. pylori infection may cause high fever. The eradication of H. pylori infection is very much related to the regular use of medication, patients should follow the doctor’s instructions when using medication, do not stop or change the dose of medication without authorization. Pay attention to rest, reasonable planning of work and rest time, do not stay up late, ensure sufficient sleep. It is recommended that patients with Helicobacter pylori infection go to the hospital in a timely manner and follow the doctor’s instructions for treatment to avoid delaying their condition.