H. pylori infection needs to be treated with a quadruple therapy, with common medications being two antibiotics and a bismuth and a proton pump inhibitor (PPI) medication. H. pylori infection needs to be treated with 4-combination therapy, two antibiotics, including amoxicillin, clarithromycin, levofloxacin, furazolidone, metronidazole, tetracycline, etc.; common bismuth agents include bismuth complex bismuth aluminate tablets, bismuth potassium citrate, colloidal bismuth pectin, etc.; and commonly used PPIs include omeprazole, pantoprazole and lansoprazole. The two antibiotics are not chosen for use randomly; the appropriate antibiotic will be chosen based on the patient’s physical condition, the extent of the condition, and a history of allergy to some medications. Generally the preferred medication is amoxicillin combined with one of the medications levofloxacin, furazolidone, metronidazole, or tetracycline, but if you are allergic to amoxicillin, you can choose tetracycline combined with one of the medications metronidazole or furazolidone. If you are diagnosed with Helicobacter pylori infection, you should use the medication under the guidance of your doctor.