Helicobacter pylori infection can be cured by a few people, such as children, but most of them need regular treatment to completely clear the infection. The incidence of H. pylori infection in children is low, and there are usually no obvious symptoms after the disease. With the growth of age, the body’s bacterial flora will be gradually perfected, and self-healing can be realized through the usual reasonable diet, healthy eating, and strengthening physical exercise and other ways of enhancing the physical fitness. The standardized treatment method is quadruple therapy, i.e., two antibacterial drugs, one proton pump inhibitor, and one bismuth agent. Proton pump inhibitors such as omeprazole, adverse effects mainly include nausea and vomiting, liver and kidney insufficiency should be used with caution. Antibacterial drugs such as metronidazole and amoxicillin, and bismuth agents such as bismuth potassium citrate can cause allergic reactions, dizziness, insomnia and other adverse reactions, and are contraindicated in pregnant and lactating women. The presence of Helicobacter pylori infection, if not treated in time can lead to peptic ulcer, gastritis, gastric cancer, etc. It is recommended that patients consult a doctor in a timely manner, standardize the treatment, and use the drugs under the guidance of a doctor or pharmacist, not self-medication, so as not to cause adverse reactions. Usually, you should pay attention to oral hygiene, rinse your mouth more often after meals, and sterilize tableware regularly.