There is no best and fastest way to get rid of phlegm in a two year old baby. Baby phlegm may be caused by acute upper respiratory tract infection, pneumonia, etc., need to be taken according to the cause of the general treatment, medication and so on. 1. Acute upper respiratory tract infection: If it is a viral infection, the main thing is to drink more water, let the baby rest more, when the baby coughs when the appropriate pat on the back, to promote coughing up phlegm. If combined with bacterial infection, generally need to apply antibiotic drugs such as cefixime treatment. 2. Pneumonia: for bacterial pneumonia, generally need to take cephalosporin or penicillin antibiotic drugs. For mycoplasma infection caused by pneumonia, need to take macrolide antibiotic drugs, such as clarithromycin, azithromycin and so on. In addition, expectorant drugs can be taken when the baby’s phlegm is more abundant, such as aminoglutethimide, aminoglutethimide hydrochloride and other drugs. All of the above drugs should be used under the guidance of a doctor, avoid self-medication. Two-year-old babies with excessive phlegm are recommended to seek prompt medical attention and be evaluated and treated by a specialist.