The first-line drugs for treating hypertension, including calcium antagonists, beta-blockers, angiotensin-converting enzyme inhibitors, angiotensin receptor antagonists, and diuretics, do not injure the kidneys and can be taken for a long time.
According to China’s guidelines for the treatment of hypertension, the first-line drugs for hypertension include calcium antagonists (e.g., amlodipine), beta-blockers (e.g., metoprolol), angiotensin-converting enzyme inhibitors (e.g., Benadryl), angiotensin receptor antagonists (e.g., valsartan), and diuretics (e.g., hydrochlorothiazide). These drugs are not detrimental to the kidneys, of which angiotensin-converting enzyme inhibitors and angiotensin receptor antagonists also have the effect of lowering urinary protein and protecting renal function, which is especially suitable for diabetic nephropathy patients.
However, angiotensin-converting enzyme inhibitors and angiotensin receptor antagonists are contraindicated in bilateral renal artery stenosis, pregnant women and those who are allergic to the product, and blood creatinine more than 265μmol/L need to be used with caution, may aggravate the deterioration of renal function, and need to be used under the guidance of a physician.
Hypertension is a common disease, chronic disease, suffering from high blood pressure need to go to the hospital, under the guidance of a physician to take antihypertensive drug treatment.