Chest discomfort and occasional coughing after sleeping, consider respiratory diseases such as trachea and bronchus, digestive diseases such as reflux esophagitis, and circulatory diseases such as coronary heart disease. 1. Respiratory diseases: acute bronchitis/bronchiolitis, mostly in the cold season, may manifest as chest discomfort, chest tightness and shortness of breath, accompanied by coughing and coughing up phlegm at night; cough variant asthma, patients may experience episodes of coughing accompanied by chest discomfort; pleural effusion, patients may experience chest pain, chest discomfort, falling asleep and lying down may lead to the diaphragm uplift, reduced lung capacity and coughing. 2. Digestive system diseases: reflux esophagitis, typically characterized by reflux, heartburn, retrosternal pain, chest discomfort, is the most common cause of non-cardiac chest pain. In addition, if the reflux violates the bronchial tube, it can cause cough and other extraesophageal symptoms. 3. Circulatory system diseases: such as coronary heart disease, patients often have chest discomfort symptoms, such as precordial pain, can be radiated to the left shoulder, left arm medial, mostly in the labor or emotional excitement; occasionally accompanied by cough symptoms. It is recommended that patients with the above symptoms go to the relevant departments of the hospital in a timely manner, under the guidance of a professional doctor, complete the relevant examinations, so as to clarify the diagnosis of the disease and receive standardized treatment.