There is no definite answer to the question of how many years it takes for osteoarthritis of the knee to progress from early to advanced stages. There is a great deal of individual variability in the progression of the disease, and it is not possible to generalize; some may last only 3 to 5 years, while others may last 10 to 20 years. The progression of osteoarthritis of the knee has individual variability and is related to the control of the cause of the disease. If the cause of the disease is well controlled or lifted, along with functional exercises, the disease may progress more slowly and the progression time will be prolonged. If the cause of the disease is not resolved or is poorly controlled, the disease may progress very quickly, as quickly as a few months. When patients are diagnosed with osteoarthritis of the knee, they should actively cooperate with the doctor to receive professional treatment, pay attention to daily protection of the knee joint, reduce the weight of the body, avoid running, jumping, climbing and other unfavorable sports for the knee joint, and actively cooperate with the functional exercise, which may prolong the time of progression of the disease and slow down the development of the disease.