Propylthiouracil tablets causing liver damage should be discontinued immediately and prompt medical attention should be sought for immediate hepatoprotective treatment. Propylthiouracil belongs to the antithyroid drugs, which are commonly used in the clinic to treat various types of hyperthyroidism. After taking it, various hypermetabolic symptoms caused by hyperthyroidism can be significantly improved. Due to the individual differences of patients, some patients may experience liver function damage during the course of taking propylthiouracil treatment, resulting in drug-induced hepatitis, abnormal elevation of gammaglutamyltransferase, and elevation of total bilirubin, and so on. Once these symptoms occur, patients should stop taking propylthiouracil immediately. Promptly consult the doctor, under the guidance of the doctor to use shark liver alcohol and other liver-protecting drugs for treatment, after the liver function returns to normal, according to the patient’s situation to choose to continue to use propylthiouracil or change other drugs for the treatment of hyperthyroidism. Therefore, in the process of treating hyperthyroidism, in order to prevent adverse reactions, it is best to regularly review, dynamically observe the changes in the body, discomfort follow-up.