Lymph nodes in the mesentery with a size of 1 cm are usually considered to be related to infections, colon cancer and other diseases, and need to go to the hospital for further examination to clarify the cause of the disease, and then consult the doctor in time. 1. Infection: It is usually due to infection in upper respiratory tract, which, along with blood circulation, causes pathogenic bacteria to reach the area of mesenteric lymph nodes, thus causing the phenomenon of mesenteric lymph nodes with a size of 1 cm. Infection may cause fever and other symptoms, which can be treated with drugs such as levofloxacin tablets and amoxicillin capsules as prescribed by doctor. 2. Colon cancer: it is usually due to the fact that colon cancer has begun to metastasize and metastasize to mesenteric lymph nodes, thus causing the phenomenon that mesenteric lymph nodes are 1 cm in size. Colorectal cancer usually has symptoms such as abdominal distension, abdominal pain, indigestion, etc. It can be treated by surgery such as radical resection of transverse colon. If the phenomenon of mesenteric lymph nodes with 1 cm size is found, it may also be related to other diseases, such as rectal cancer, etc. It is suggested that patients should go to hospital for further systematic examination, and give treatment as soon as possible so as to avoid delaying the condition.