Mannitol injection has diuretic, decongestant, dehydrating, and intracranial pressure lowering effects. 1, Used to treat cerebral edema from various causes, lower intracranial pressure, and prevent brain herniation. 2, Lower intraocular pressure, which can effectively lower intraocular pressure, is applied when other intraocular pressure lowering is ineffective or in preparation for intraocular surgery. 3, Osmotic diuretic used to identify prenephrotic factors or oliguria caused by acute renal failure. It can also be used to prevent acute tubular necrosis due to various causes.4. As an adjuvant diuretic measure for the treatment of nephrotic syndrome and ascites, especially when accompanied by hypoproteinemia.5. For certain drug overdose or toxic poisoning, mannitol can be given to promote excretion of the substance and prevent nephrotoxicity.