There are venous wall thickening and arterial wall thickening. Venous vascular wall thickening can be treated with general treatment, medication, surgery, etc. Arterial vascular wall thickening can be treated with different medications. 1. Venous vascular wall thickening (1) General treatment: appropriate exercise to increase venous blood return, avoid sitting and standing for a long time. (2) Drug therapy: drug therapy only plays an auxiliary role, commonly used drugs are flavonoids, hepatic saponins, can also choose aspirin and so on to relieve symptoms. (3) Surgical treatment: surgical treatment should be based on the patient’s thickened parts of different choices of different surgeries, such as thickening of blood vessels in the lower limbs can choose saphenous vein ligation. (4) Physical therapy: laser or radiofrequency can be used to relieve the patient’s symptoms. 2. Arterial wall thickening (1) Statin lipid-lowering drugs: such as simvastatin, etc., to control the patient’s blood lipids and slow down the progress of the disease. (2) Antiplatelet drugs: commonly used aspirin, which can prevent platelet aggregation and avoid the formation of blood clots. (3) Vasodilator drugs: such as sagrexate, etc., to allow the narrow part of the blood vessel to expand and improve blood supply. If the examination shows thickening of the blood vessel wall don’t panic, you should consult your physician in time and standardize the treatment under his professional guidance.