Pancreatic density unevenly reduced is good or bad, but also to determine the specific causes, physiological factors are not a big problem, pathological factors should be alert to malignant lesions. 1. Physiological factors: physiological factors are often seen in patients who are overweight and obese, long term high calorie and high fat food, due to the increase in triglyceride levels, which can be deposited in pancreatic tissues, so part of the population can have ectopic fat accumulation and pancreatic hypodensity foci. 2. Pathological factors: Pathological factors should be alert to the presence of pancreatic malignant tumors, especially be alert to the occurrence of lymphatic metastasis in patients with pancreatic malignant tumors; uneven pancreatic density may also indicate the presence of pancreatitis, which requires further examination. When pancreatic hypodensity is found, it is recommended to consult the gastroenterology department or hepatobiliary and pancreatic surgery department of regular hospitals to clarify the cause.