Patients in the use of injectable methylprednisolone sodium succinate treatment generally 4~6 hours after the clinical response can be observed, while the treatment of asthma can be observed in 1~2 hours, the specific onset of action time may vary depending on the patient’s physical and medical factors. Methylprednisolone sodium succinate for injection is the active ingredient of methylprednisolone, methylprednisolone belongs to the glucocorticoid hormone, has strong anti-inflammatory, anti-allergic effect, under normal circumstances, the clinical response can be observed in 4~6 hours after the administration of methylprednisolone in the treatment of asthma, the efficacy of methylprednisolone can be observed 1~2 hours after the administration of the drug. Methylprednisolone is mainly metabolized by the liver after entering the human body, and the metabolism speed is related to the patient’s liver function. The specific onset of effect of treatment with this drug may vary according to the dosage of the drug, the individual’s physical condition, the specific condition, the type of the disease and other factors, and the dosage of the drug needs to be gradually reduced after a few days of treatment with methylprednisolone. Adverse reactions such as infections, electrolyte disorders, and peptic ulcers may occur after administration of the drug. Systemic mycobacterial infections and known hypersensitivity to the components of the drug are contraindicated. Pay attention to sodium restriction and potassium supplementation during the administration of the drug, monitor for infections and gradually reduce the dose before stopping the drug. Methylprednisolone sodium succinate for injection should be used under the guidance of a physician, and patients are advised to go to the relevant departments of regular hospitals for detailed consultation.