Hot hand pain may be due to allergies, trauma, nerve compression, viral infections, etc. There is no such thing as the fastest way to relieve it, and you need to take corresponding treatment measures according to the cause of the disease, including saline rinsing, the use of drugs such as celecoxib, hydrocortisone, loratadine, or acyclovir. 1. Allergy: Commonly found in chili peppers, hair dyes, cosmetics, etc., which can be immediately washed with saline and iced. If symptoms such as rash and redness appear at the same time, you can apply hydrocortisone cream or take anti-allergy drugs such as loratadine. 2. Trauma: such as abrasions, pressure injuries, fractures, etc., you can take anti-inflammatory pain relievers such as Celecoxib orally, and if there is bleeding skin, you need to disinfect it with iodophor or alcohol. 3. Nerve compression: including elbow tube syndrome, carpal tunnel syndrome, cervical spondylosis, etc., the onset of compression of nerves leading to hand pain, can be used through the use of prednisolone acetate and other hormone drugs, ibuprofen and other anti-inflammatory drugs, to play a role in reducing swelling, analgesia and so on. 4. viral infection: herpes zoster, available wet towel cold compresses or glycerine lotion pain and swelling, taking acyclovir and other antiviral drugs and acetaminophen or tramadol and other analgesic drugs. If the symptoms of spicy hand pain are serious or last for a long time, it is recommended to seek medical attention as soon as possible, with the help of a doctor for targeted treatment.