Anxious depression should mean that the patient meets the diagnostic criteria of depression and also has mild anxiety, but does not meet the diagnostic criteria of anxiety disorder. For treatment, you can first choose some antidepressants with obvious sedative-hypnotic effects, such as doxepin, trazodone, paroxetine, mirtazapine, etc. You can also apply antidepressants in combination with benzodiazepine anxiolytics for a short period of time, such as diazepam, alprazolam, levopiridone, etc. Benzodiazepine anxiolytics have a rapid onset of action and help relieve the symptoms of anxiety depression that exist in patients with anxiety depression. Acute anxiety attacks and insomnia are also symptoms. Non-benzodiazepine anxiolytics, such as buspirone and tandospirone, can also be used in combination and take a few days to work. If the patient’s anxiety is severe, manifesting as extreme nervousness, fidgeting, impatience, and irritability. A short-term combination of a mood stabilizer, such as sodium valproate, or a small dose of an atypical antipsychotic, such as olanzapine, quetiapine, etc., may also be used.