The direct consequence of low insulin levels is an increase in blood sugar because insulin is the only hormone in the body that can lower blood sugar, so a decrease in the level of insulin secretion will lead to an increase in blood sugar, leading to diabetes. Moreover, diabetics with low insulin levels usually have type 1 diabetes or adult-onset diabetes. These patients need to use insulin to control blood glucose throughout their lives, and oral hypoglycemic drugs are not effective in treating this type of patient because insulin deficiency is very likely to lead to diabetic ketoacidosis. In addition, insulin has the role of promoting protein and fat synthesis, low insulin levels of patients will be thin, coupled with the consumption of high blood sugar will be even more pronounced body thinning.