Two and a half months after high-risk sex, a slightly elevated white blood cell count and a lowered eosinophil percentage may be associated with an infection or a sexually transmitted disease. If the infection, the blood routine may appear slightly elevated white blood cell count, eosinophil percentage decreased, but also need to be judged from the patient’s physical signs, whether there is fever and other manifestations of infection, which may not have anything to do with high-risk sex, it is recommended to improve the relevant auxiliary examination. Syphilis, condyloma acuminatum, AIDS and other sexually transmitted diseases, can not simply through the blood routine to determine, but also need to type specific tests to assist in the judgment, such as condyloma acuminatum need to do acetic acid white test, histopathological examination. AIDS need to check the human immunodeficiency virus (HIV) antibody, CD4 + T lymphocytes, HIV nucleic acid test and so on. It is recommended to try to avoid high-risk sex, after high-risk sex, it is recommended to go to the hospital in a timely manner, especially the need for AIDS and other sexually transmitted diseases, to avoid delaying the condition.