Acid reflux with bad breath may be caused by Helicobacter pylori infection, which needs to be eradicated using quadruple therapy; it may also be caused by gastroesophageal reflux disease (GERD) or chronic gastritis combined with oral diseases (e.g., tooth decay, caries, periodontitis, etc.), which need to be treated separately for the causes. 1. Helicobacter pylori infection: After it is clear that there is Helicobacter pylori infection, it can be eradicated by using quadruple therapy under the guidance of specialized physicians, including one proton pump inhibitor, one bismuth and two antibiotics, commonly used are clarithromycin, amoxicillin, bismuth potassium citrate, omeprazole and so on. 2. Gastroesophageal reflux disease or chronic gastritis combined with oral diseases: gastroesophageal reflux disease or chronic gastritis can be acid reflux manifestations, can be used in accordance with the doctor to inhibit the secretion of gastric acid such as omeprazole and other proton pump inhibitors, magnesium aluminum carbonate and bismuth citrate potassium and other protection of the gastric mucosa; oral diseases such as dental cavities, dental caries, periodontitis, etc., which can lead to symptoms of halitosis, can be prescribed by the doctor for the treatment of the specific cause of the disease. Acid reflux with bad breath can also be seen in other diseases, it is recommended to consult a doctor in a timely manner, under the guidance of the doctor for treatment, so as not to delay the condition.