The term “great aunt” generally refers to a woman’s period. Painkillers do not usually affect menstruation; they are only effective for the current menstrual cramps. Menstrual cramps are usually caused by the prostate gland secretion of the uterus contraction spasmodic pain, the need to use non-steroidal anti-inflammatory drugs, such as ibuprofen delayed-release tablets, to inhibit the synthesis of prostaglandins to play the effect of pain, but also belladonna tablets such as drugs, to play the effect of antispasmodic. The side effect of pain medication is that it is irritating to the stomach and tends to cause stomach upset, such as nausea and vomiting, without the side effect of causing menstrual irregularities. When menstrual cramps take once or twice pain medication usually does not affect menstruation and the body. Once the patient himself has gastrointestinal ulcer symptoms, it is best not to take painkillers to avoid causing ulcer aggravation or even stomach bleeding phenomenon. During the period of taking painkillers, if there is any discomfort, you need to go to the hospital in time to get a clear diagnosis, and the doctor will formulate an individualized diagnosis and treatment plan according to the specific condition, so as to avoid delaying the condition. The use of painkillers should be strictly in accordance with medical advice.