After the hemorrhoid cream patients feel more pain, the main consideration is that the patient itself has a ruptured external hemorrhoid or anal fissure. After the medicine will stimulate the wound, which will lead to increased pain. Because the anal fissure and external hemorrhoid rupture part belongs to the part below the tooth line, mainly by the somatic nerve innervation, for the pain is particularly sensitive, after using the medicine pain will be more obvious. It is recommended that this situation can choose diclofenac sodium internal plug anus, to play the effect of anti-inflammatory pain relief, or direct intramuscular injection of clonoxicam to relieve pain. Usually after 3-4 days of continuous medication, this symptom will be significantly improved. Because the hemorrhoidal cream itself has the effect of expelling rotting muscle and stopping bleeding, if the wound reaches healing or grows fresh granules, the pain will also be significantly improved. Usually patients should also pay attention to the dryness and hygiene of the perianal area, it is generally recommended that after defecation or before bedtime you can use warm salt water or anal wash sitz bath.