Sequelae of megacolon, such as leakage of stool, usually do not last for a lifetime. Surgery is the preferred treatment for megacolon, and most of the patients can recover well after the surgery, but a few patients may have sequelae such as leakage of stool, recurrent enterocolitis, and defecation disorders. The leakage of stool after megacolon surgery may be mild or severe, and most of the patients can get better half a year after surgery, and it can disappear one year after surgery. This is mainly due to the fact that megacolon surgery needs to remove the diseased intestinal canal, which may damage the rectum and anal canal muscles and nerves, and may disrupt the defecation process, which may easily cause leakage. Most patients recover well after surgery, but if the leakage doesn’t return for a long time, you can report to your doctor in time. Patients are advised to go to the hospital for regular checkups and follow the doctor’s instructions for good recovery.