There is no contraindication to nucleic acid testing, just a few things to keep in mind. Nucleic acid testing is mainly used to check for the presence of viral infections and is mostly done by taking a throat swab or nasal swab. Before the test, you need to pay attention to maintaining oral and nasal hygiene, relaxation, and also need to wear a mask. In addition, there are other tests such as sputum, genital secretions, blood, feces, urine, etc. The precautions are not exactly the same, so it is recommended to consult with your doctor or testing unit in advance. 1. Maintain oral and nasal hygiene: Pay attention to keeping the oropharynx and nasal cavity clean so as not to cause inconvenience in sampling or affect the test results. Smoking, drinking or eating a lot of food are not recommended near the time of sampling, and you can rinse your mouth properly with water. Taking a throat swab may cause nausea and dry heaving in some people, so do not eat too much before the test so as not to induce vomiting on a full stomach. 2. Relaxation: Nucleic acid test sampling can cause a certain degree of discomfort to the examinee, especially to the more sensitive to physical stimulation of the crowd, it is recommended to try to relax before the test. Over-concentration or over-stress may make the stimulus more obvious, but the discomfort will subside soon after the test is completed, so there is no need to worry too much. 3. Wear a mask: You need to wear a mask before and after the nucleic acid test. Nucleic acid test usually produces a gathering of people, in order to avoid cross-infection, it is recommended to wear a mask before and after the nucleic acid test.