Rheumatoid rheumatoid arthritis, juvenile idiopathic arthritis and rheumatoid arthritis, the difference is mainly for the cause of the disease and clinical manifestations. 1. Different etiology: the etiology of juvenile idiopathic arthritis is still unclear, and it is believed that the infection induces abnormal immune response in susceptible people; the etiology of rheumatoid arthritis has not yet been clarified, and a large number of researches have shown that it is related to genetic factors, environmental factors and so on. 2. Clinical manifestations (1) Juvenile idiopathic arthritis occurs at the age of less than 16 years, and the symptoms of arthritis are chronic synovitis that lasts for more than 6 weeks, and the joint symptoms are pain, swelling and other arthritic manifestations. Some patients may develop synovial lesions at an early stage. The manifestations of juvenile idiopathic arthritis are more diverse, and can be manifested as monoarthritis, polyarthritis, or lesions involving the eyes. (2) Rheumatoid arthritis mostly develops at the age of 35 to 50 years, and is more common in women than in men. Clinical manifestations include symmetrical involvement of multiple joints, commonly metacarpophalangeal joints, wrist joints, etc., with joint pressure and pain, accompanied by morning stiffness. With the aggravation of the disease, joint deformity may occur. It is recommended that patients seek timely medical treatment, and the specific identification of the disease needs to consult a doctor.