Children’s nuclear magnetic suggests demyelinating lesions, is considered to be more serious, the etiology is still unclear, the clinical manifestations are varied, and usually treated with drugs. The etiology of demyelinating lesions is still unclear, mainly including congenital and acquired, congenital mainly refers to cerebral white matter dystrophy, mostly seen in children, and acquired may be related to infection, chronic inflammation, trauma and so on. Clinical manifestations are diverse, mainly limb numbness, dizziness, headache, convulsions, etc. There also exist people without obvious symptoms, mainly found by cranial imaging. Drug therapy for demyelination in children mainly includes hormones such as methylprednisolone and immunomodulators such as gammaglobulin. Most of the children have a good prognosis, but a few may have a relapse. Consult your physician for specific treatment.