If a depressed person continues to take medication and actively cooperates with the doctor, he or she can usually get relief in about 12 weeks and return to normal in about six months. Under normal circumstances, how long it takes for depression to return to normal needs to be decided according to the severity of the symptoms, the amount of medication and the patient’s physical condition, etc., and cannot be generalized. Depression is a mental illness characterized by low mood, loss of interest, decreased energy and general fatigue and other symptoms, usually can be psychological, drug and physical therapy, regardless of which treatment, should be carried out under the guidance of a doctor, not blind treatment, in life with friends and relatives to keep in touch with more communication, usually can be relaxed by walking, watching movies, going out to visit and other ways. Depression patients should go to professional hospitals for treatment as early as possible, as well as regular review to avoid adverse consequences.