The difference between the 2-valent, 4-valent and 9-valent HPV vaccines is that the subtypes are different, the people who use them are different, and the prices are different. 2-valent vaccine is used to prevent HPV type 16 and 18 viruses, and is suitable for women between 9-25 years old, and the price is relatively cheaper. 4-valent vaccine includes viruses of type 6 and 11 in addition to the above two, and is suitable for men and women between 20-45 years old, and the price is also more expensive than the 2-valent vaccine. The 9-valent vaccine can effectively prevent type 16, 18, 6, 11, 31, 33, 45, 52, etc. It can prevent precancerous lesions of the cervix and 2/3 of the vagina and vulva, with a prevention rate of more than 95%, which is the highest degree of HPV vaccine development and currently the highest price.