With symptoms of chronic coughing and wheezing, it is likely to be chronic bronchitis. A chest CT is needed to confirm the diagnosis. If it is indeed a case of chronic bronchitis, anti-infective treatment is needed during the acute exacerbation, first of all, go for sputum culture as well as drug sensitivity test. According to the type of infection, choose the appropriate antibiotics for anti-infection treatment. Secondly, some cough and phlegm and asthma treatment, cough and phlegm drugs, you can choose aminobromoterol oral solution or aminobromine hydrochloride, compound fresh bamboo lee liquid effect is also good. As for asthma medication, you can nebulize inhalation of some bronchodilators and glucocorticoids for asthma, such as nebulized inhalation of budesonide and terbutaline sulfate. Another long-term cough, wheezing, may be caused by asthma, the need for long-term anti-asthma treatment, such as bedtime can be chewed a montelukast sodium chewable tablets, usually can be a long-term inhalation of XinBiKe relief symptoms.