First-time users may experience dizziness, nausea, vomiting, and in severe cases, cold sweats, decreased blood pressure, and heartburn. Allergy can occur in special body types and is related to biocompatibility. The side effects of hemoperfusion are related to its characteristics. Most of the hemoperfusion currently used achieves its function through resin adsorption, which has a certain adsorption effect on platelets in addition to the adsorption of toxins, and therefore can have a certain effect on the patient’s platelets. In addition, hemoperfusion requires high doses of anticoagulant drugs, and the patient’s coagulation function is altered in the short term. It is recommended that the patient’s coagulation function and platelet count be evaluated before and after hemoperfusion to rule out the possibility of bleeding.