Ultrasound shows that the liver parenchyma echogenicity is slightly coarsened, which is mainly considered as fatty liver, cirrhosis, etc., and all of them should be actively cooperated with the treatment, and cirrhosis is a more serious condition. 1. For normal people, if ultrasound shows slightly coarsened liver parenchyma echogenicity, the most likely cause is fatty liver. Lipids can be further examined, and if elevated lipids occur, active control of lipids is needed. The first step should be lifestyle changes, such as a light diet and moderate exercise. If the blood lipid level is high and cannot be lowered by lifestyle changes, oral lipid-lowering drugs, such as fenofibrate tablets, are needed. 2. For people with a history of chronic hepatitis, if ultrasound reveals thickening of liver parenchyma echogenicity, it is necessary to pay attention to it, which may be caused by cirrhosis. It is necessary to improve liver hardness test and liver function test to clarify the diagnosis. If the diagnosis of cirrhosis is confirmed, active treatment is needed to avoid the continued progression of cirrhosis. Patients need to go to the hospital in a timely manner to clarify the diagnosis and treatment plan, and use drugs under the guidance of the doctor, avoid self-medication.