Whether the bilateral lobes of the thyroid gland with multiple nodules are serious or not is objectively analyzed based on factors such as the volume, size and different nature of the thyroid nodules: i. If the thyroid nodules are large in size, accompanied by local symptoms of tracheal, esophageal and nerve compression, the patient presents with clinical manifestations such as hoarseness, choking and coughing with water and breathing difficulties. Ultrasound examination reveals that the nodule is accompanied by obvious calcification, rich blood flow, and the aspect ratio is greater than the first malignant sign. In this case, the nodule is considered to be cancerous. If the nodule is not surgically removed in time, it may cause extensive metastasis of cancer cells and serious complications. If the nodules in the bilateral lobes of the thyroid gland are small in size, ultrasound examination indicates that the nodules have clear borders, regular shape and uniform echogenicity. In this case, the nodules are considered to be benign lesions, and they do not have obvious pressure symptoms and will not cause serious impact on the human body, so close observation is recommended and surgery is not needed for the time being.