Ischemia-modified albumin is an ischemia-modified albumin in which the amino acid sequence of serum albumin is disrupted by free radicals and other substances, resulting in a change in the binding ability of albumin and transition metals, and this albumin, whose binding ability with transition metals is altered by ischemia, is called ischemia-modified albumin. It is a relatively new marker of myocardial ischemia and can be used for early detection of myocardial ischemia by measurement of ischemia-modified albumin. It is highly sensitive to myocardial ischemia and is particularly suitable for the diagnosis of myocardial ischemia in cases of negative troponin test and for the exclusion of myocardial ischemia in patients with chest pain who have normal electrocardiogram. Currently, ischemia-modified albumin and troponin can be used together as early screening indicators for myocardial infarction in clinical practice, which can lead to an increase in the sensitivity of myocardial infarction and can advance the time of diagnosis.