Uremia actually occurs when there is an increase in urine due to a deficiency of argipressin or an insensitivity of the kidneys to argipressin caused by certain diseases of the kidneys. The appearance of uraemia is characterized by frequent urination, in addition to a high volume of urine, which will appear significantly higher than normal, both during the day and at night, a lot of urination. And unlike the frequent urination caused by other diseases, the frequent urination caused by uremia will be accompanied by an increase in urine output. Normal people’s urine volume is about 1000-2000ml per day, but patients with uremia often have a significant increase in urine volume in addition to the obvious increase in the number of times they urinate, even above 5000ml. Frequent urination with a significant increase in urine output is a typical symptom of uremia.