We often encounter patients with osteoarthritis of the knee who have been suffering from pain for years or decades because of the risk of surgery, and only come to surgery when they are unable to walk or take care of themselves because of the obvious deformity of the knee. Some patients even miss the best time for surgery and live in wheelchairs, which is a great pity. Therefore, it is important for patients to understand that joint diseases should be seen as early as possible, and that the current treatment options are mature and varied. Osteoarthritis of the knee is a common chronic degenerative joint disorder in the middle-aged and elderly population, with a prevalence of up to 90% in people over 65 years of age, about 60% of whom have symptoms. Pain is most common and is activity-related, starting with painful activity and then persistent pain, with late onset of nocturnal pain and even waking up in pain, in addition to a fairly high disability rate due to joint swelling, deformation and restricted movement. Early to mid-stage knee osteoarthritis can improve symptoms and reduce joint pain with NSAIDs and chondroprotective agents, but this only relieves symptoms and does not stop and reverse the disease process. In elderly patients with osteoarthritis of the knee, if the pain is severe and regular conservative treatment is ineffective and function is significantly limited, artificial knee replacement surgery can be considered, which commonly includes arthroscopic surgery and artificial joint replacement surgery. Arthroscopic surgery is used for early-stage joint disease without severe structural damage, while artificial joint replacement surgery is the best treatment for end-stage joint disease. Currently the prosthetic survival rate is over 95% for 10-15 years after total knee replacement, with an average survival of about 20 years. 60-80 year old patients with knee osteoarthritis are the best age for surgery, and a single surgery can be beneficial for life. Artificial knee arthroplasty has evolved to meet the needs of patients with varying degrees of joint pathology. For patients with milder lesions, total knee surface replacement is an option. This procedure is the most widely used prosthesis because of its thoroughness, efficacy, and long life of the joint. Usually, you can get out of bed 2-3 days after the artificial joint replacement and practice walking with a walker or crutches, and you can walk independently in 2 to 3 weeks, and you can basically resume normal activities completely 3 months after the surgery. There are more than 200,000 artificial knee replacements each year in the United States, but less than 20,000 in China. With the relentless pursuit of quality of life, it is believed that more and more patients with osteoarthritis will choose to undergo joint replacement surgery at the right time.