The spleen is the largest immune organ in the body, accounting for 25% of the total lymphoid tissue in the body, containing a large number of lymphocytes and macrophages, and is the center of cellular and humoral immunity in the body, exerting anti-tumor effects through a variety of mechanisms. The spleen also has the functions of storing blood and regulating blood volume, destroying senescent blood cells, blood filtration and producing immunoglobulins, complement and other immune substances. Because the spleen is located deep under the left quadrant of the rib cage and is closely adjacent to the fundus of the stomach, the splenic flexure of the colon and the tail of the pancreas, open surgery is relatively difficult to reveal, the incision is long, and postoperative pain and recovery are slow. With the increasing maturity of laparoscopic instruments and techniques, laparoscopic splenectomy has become the gold standard for splenectomy in hepatobiliary surgery, following laparoscopic cholecystectomy. What are the advantages of laparoscopy over conventional splenectomy? Except for the giant spleen in cirrhosis, laparoscopic splenectomy can be completed with only three to four holes, minimizing the incidence of infection and incisional hernia in the traditional incision. Secondly, the laparoscopic field of view is open and clear, and the operative field is clear for ambassadorial operation, which can avoid surrounding organ damage to the maximum extent. Furthermore, the laparoscope can reach the narrow space around the spleen, and splenectomy can be successfully completed by only dealing with the arteriovenous vessels entering and leaving the splenic hilum, making laparoscopic splenectomy very safe. The procedure is less painful after surgery, facilitates early movement, deep breathing and coughing up sputum, and minimizes the incidence of atelectasis and pulmonary infections, making it suitable for most patients. Which spleen diseases require surgery? In addition to traumatic injuries such as car accidents that result in spleen rupture requiring emergency surgery, elective splenectomy is also required for: 1. spleen tumors: primary tumors of the spleen are relatively rare, but a clear diagnosis of either benign or malignant often requires surgery. 2, wandering spleen: congenital overgrowth of the spleen tip can cause torsional necrosis of the spleen by excessive activity. 3.Hematopoietic system diseases: Hematologic diseases that do not respond to medical treatment require splenectomy, such as primary thrombocytopenic purpura and congenital hemolytic anemia. 4. Parasites: destruction of spleen tissue structure caused by parasites, splenomegaly secondary to hypersplenism, and portal hypertension caused by infection.