Treatment for cholesteatoma otitis media is medication and surgery. Medications cannot make cholesteatoma disappear, but they can control the infection and relieve some of the symptoms. Antibiotics such as amoxicillin and cefuroxime are commonly used for anti-infection treatment. Surgical treatment can completely remove the cholesteatoma and necrotic bone tissue and skin, improve hearing, and prevent the occurrence of otogenic intracranial and extracranial complications. Once found, surgical treatment should be carried out as early as possible, and commonly used surgical methods such as external otorhinoplasty, tympanoplasty, mastoidectomy and so on. When symptoms such as pus in the ear canal, tinnitus, stuffy ears and hearing loss occur, you should go to the hospital in time and receive standardized treatment under the guidance of your doctor. The above medicines should be used reasonably under the guidance of doctors, and avoid purchasing and using them on your own.