Normal human blood calcium is 2.25-2.75mmol/L, when the blood calcium is higher than 2.75mmol/L is hypercalcemia, when the blood calcium is greater than 3.75mmol/L can occur hypercalcemic crisis. The clinical manifestations of hypercalcemic crisis usually include the following: a. Gastrointestinal symptoms are aggravated, high calcium can cause anorexia, nausea, vomiting, abdominal distension, constipation and other symptoms, and the above gastrointestinal symptoms will be aggravated in hypercalcemic crisis. Second, the nervous system, hypercalcemia can cause weakness, lethargy, inattention, hypercalcemia crisis can appear the above symptoms aggravated, and appear drowsiness, coma and other impaired consciousness. Cardiovascular system, hypercalcemia can cause various cardiac arrhythmias, especially fatal arrhythmias, which can lead to cardiac arrest. Fourth, the urinary system, hypercalcemia can trigger urinary stones, leading to polyuria, increased nocturia, and serious involvement of kidney function, leading to renal insufficiency.