Platelet pressure volume is the volume of platelets in peripheral blood as a percentage of blood volume. Low platelet pressure volume is mainly caused by a decrease in the number of platelets in peripheral blood. In clinical practice, there are various reasons for the decrease in platelet count, the most common being the decrease in platelet count caused by hematologic disorders. Aplastic anemia is the most likely cause of thrombocytopenia, because aplastic anemia is a bone marrow hematopoietic failure disease, due to the damage of hematopoietic stem cells, they cannot produce normal platelets, which will lead to a decrease in platelet count and thus a low platelet pressure. This disease can be seen in acute leukemia, where the normal bone marrow hematopoietic function is destroyed due to the proliferation of leukemic cells in the bone marrow, and the number of platelets produced is reduced, which also results in a low platelet pressure. There is also immune thrombocytopenia, a condition in which the number of platelets is reduced due to excessive destruction of platelets in the peripheral blood, and a low platelet pressure volume can also occur.