Pruritus is considered when itching occurs throughout the body without lesions. The etiology of pruritus is complex and can be divided into intrinsic and extrinsic factors. Intrinsic factors, such as individuals with different degrees of skin hydration, dry skin prone to pruritus; mental factors, such as tension, anxiety, fear, excitement and other emotions, can lead to pruritus; systemic diseases, such as liver system diseases, kidney system diseases, blood diseases, endocrine and metabolic diseases, malignant tumors, parasitic infections, etc.; pregnancy, drug and food allergies, can also lead to pruritus . External factors, such as the environment, season, such as dry winter prone to itching, light stimulation, work and living environment humidity; lifestyle habits, such as excessive washing, wearing chemical fiber clothing lead to itchy skin. When itching occurs, you need to actively get rid of suspicious factors, avoid excessive scratching, washing and scalding, avoid eating irritating food, and use topical anti-itching agents and emollients, such as Furfuryl, vitamin E moisturizer. In cases of severe itching, oral antihistamines such as cyproheptadine and paracetamol can be taken.