A bilirubin of 200 μmol/L is dangerous and suggests the presence of active hepatitis, intra- and extra-hepatic obstructive jaundice, cholangiocarcinoma, hepatocellular carcinoma, liver failure, etc. Bilirubin is one of the clinical indicators of liver function. Bilirubin is one of the indicators for clinical testing of liver function, usually divided into total bilirubin, direct bilirubin and indirect bilirubin, the normal range of total bilirubin is 3.42-20.05 μmol/L, the normal range of direct bilirubin is 0-6.84 μmol/L, and the normal range of indirect bilirubin is 0-13 μmol/L. When bilirubin 200 μmol/L is detected, the result is far above the normal range. When bilirubin 200μmol/L, it suggests that acute jaundice hepatitis, chronic active hepatitis, and intra- and extra-hepatic obstructive jaundice may be present, and the condition is more dangerous. Hepatocellular jaundice leading to liver failure can also cause severe jaundice. When the above situation occurs, patients are advised to seek medical treatment in time, according to the symptoms and other examination results, to clarify the cause of the disease under the guidance of specialized physicians, and to treat the disease as early as possible so as not to delay the condition.